Digoxin is a cardiac glycoside that decreases the conduction of electrical impulses through the AV node in the heart. It also increases the force of heart contractions by binding to and inhibiting the Na+/K+ ATPase pump, which causes an increase in the level of sodium ions in the myocytes, thereby leading to a rise in the level of calcium ions. Digoxin is expressed in the foxglove plant digitalis and is then extracted for clinical use to improve the pumping ability of the heart in congestive heart failure (CHF) and to treat patients with high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat) and to stabilize atrial fibrillation and atrial flutter with rapid ventricular response.

Digoxin

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0.78

This Abmart monoclonal antibody is produced by immunizing mice with a
Digoxin-KLH.

MOUSE IgG

Human

DETECTION RANGE                      
0.2-2ng/ml

SENSITIVITY
IC50=0.5ng/mll

Stored at -20°C or below until use. Avoid repeated freezing and thawing cycles.